Monday 9 May 2011

Lorazepam tablets of the Ativan brand also contain lactose, microcrystalline cellulose, polacrilin, magnesium stearate, and colouring agents (indigo carmine—E132—in blue tablets and tartrazine—E102— in yellow tablets).

The prolonged sedation from lorazepam may, however, be an acceptable trade-off for its reliable duration of effects, particularly if the patient needs to be transferred to another facility. * Pregnancy and breast feeding – Lorazepam belongs to the Food and Drug Administration (FDA) pregnancy category D, which means that it is likely to cause harm to the developing baby, if taken during the first trimester of pregnancy. But diazepam's high lipid solubility also means it does not remain in the vascular space but soon redistributes into other body tissues. Hydrolysis of thee above product forms the desired product lorazepam. Adverse effects can include sedation and hypotension; the effects of lorazepam are increased in combination with other CNS depressant drugs. Ativan overdose symptoms may include extreme drowsiness, confusion, muscle weakness, fainting, or coma. It is dangerous to try and purchase Ativan on the Internet or from vendors outside of the United States. But diazepam's high lipid solubility also means it does not remain in the vascular space but soon redistributes into other body tissues. Lorazepam is used for the short-term treatment of anxiety, insomnia, acute seizures including status epilepticus and sedation of hospitalised patients, as well as sedation of aggressive patients. Like oxazepam, it does not require hepatic oxidation, but only hepatic glucuronidation into lorazepam-glucuronide.

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