Hydrolysis of thee above product forms the desired product lorazepam.

What happens if I miss a dose?Take the missed dose as soon as you remember. Lorazepam has relatively potent anxiolytic effects and its best-known indication is the short-term management of severe anxiety; the FDA advises against use of benzodiazepines such as lorazepam for longer than 2–4 weeks. In a group of around 3500 patients treated for anxiety, the most common side effects complained of from lorazepam were sedation (15. * Suicidality: Benzodiazepines may sometimes unmask suicidal ideation in depressed patients, possibly through disinhibition or fear reduction. S. This contrasts with the highly lipid-soluble diazepam, which, although rapidly absorbed orally or rectally, soon redistributes from the serum to other parts of the body, in particular body fat. As a result dosage recommendations for the elderly are about half of those used in younger individuals and used for no longer than two weeks. Side effects such as sedation and unsteadiness increased with age. Increasing the dose may overcome tolerance, but tolerance may then develop to the higher dose and adverse effects may persist and worsen. 5 mg, 1 mg, or 2 mg lorazepam, with some differences between countries.