An example would be the inappropriate use to relieve anxiety associated with acute severe asthma.

Lorazepam-glucuronide is more water-soluble than its precursor and, therefore, gets more widely distributed in the body, leading to a longer half-life than lorazepam. Long-term effects of benzodiazepines include tolerance, dependence, a benzodiazepine withdrawal syndrome and cognitive impairments which may not completely reverse after cessation of treatment; however, for most patients, cognitive impairment is not severe. Lorazepam is more effective than diazepam in the treatment of status epilepticus. Males and females use benzodiazepines for nonmedical purposes equally. Food and Drug Administration (FDA) or visit www. e. Also used to treat acute symptoms of vertigo and dizziness for people with MГ©niГЁre's disease. edit PharmacologyLorazepam has anxiolytic, sedative, hypnotic, amnesic, anticonvulsant as well as muscle relaxant properties. Lorazepam injectable solution is administered either by deep intramuscular injection or by intravenous injection. The likelihood of dependence is relatively high with lorazepam compared to other benzodiazepines.