6.

Lorazepam is metabolised in the liver by conjugation into inactive lorazepam-glucuronide. Lorazepam was first introduced by Wyeth Pharmaceuticals in 1971 under the brand names of Ativan and Temesta. See also: Ativan pregnancy and breastfeeding warnings (in more detail)The sedative effects of this medication may last longer in older adults. Dose requirements have to be individualized, especially in the elderly and debilitated patients in whom the risk of oversedation is greater. Do not miss any scheduled visits to your doctor. nausea and vomiting caused or worsened by psychological sensitization to the thought of being sick. Acute delirium is sometimes treated with lorazepam, but as it can cause paradoxical effects, it is preferably given together with haloperidol. Dose requirements have to be individualized, especially in the elderly and debilitated patients in whom the risk of oversedation is greater. Long-term effects of benzodiazepines include tolerance, dependence, a benzodiazepine withdrawal syndrome and cognitive impairments which may not completely reverse after cessation of treatment; however, for most patients, cognitive impairment is not severe. Do not drink alcohol while taking Ativan.